Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25393922 | 0.89 | AKR1C3 (0.39) | ALDH1A1HSD17B10HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL30338079 | 0.83 | GPR119 (0.45) | ALDH1A1CYP2C19CYP2C9HSD17B10CYP3A4 | |
| SCHEMBL25407146 | 0.83 | GPR119 (0.45) | ALDH1A1CYP2C19CYP2C9HSD17B10CYP3A4 | |
| SCHEMBL25248226 | 0.71 | MAP4K4 (0.52) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30480339 | 0.71 | MAP4K4 (0.52) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21855186 | 0.68 | HSD17B10 (0.48) | USP2ALDH1A1CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL641121 | 0.67 | CYP2C9 (0.75) | USP2ALDH1A1CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL25411360 | 0.67 | DGAT1 (0.32) | ITGB3ITGA2B | |
| SCHEMBL30503535 | 0.67 | DGAT1 (0.32) | ITGB3ITGA2B | |
| SCHEMBL29024380 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192588-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2023-06-14 | — | — | EP | disclosed |