Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25216953 | 1.00 | PDE5A (0.30) | PDE5APDE4BGLP1R | |
| SCHEMBL21223738 | 0.78 | BACE1 (0.39) | — | |
| SCHEMBL29427021 | 0.78 | — | — | |
| SCHEMBL25250237 | 0.78 | — | — | |
| SCHEMBL29698778 | 0.78 | BACE1 (0.39) | — | |
| SCHEMBL15077057 | 0.77 | CRHBP (0.39) | PDE5APDE4BGLP1R | |
| SCHEMBL23667260 | 0.76 | — | — | |
| SCHEMBL12641362 | 0.76 | LMNA (0.37) | PDE5APDE4BGLP1R | |
| SCHEMBL12569450 | 0.76 | LMNA (0.37) | PDE5APDE4BGLP1R | |
| SCHEMBL19068830 | 0.74 | GCGR (0.32) | PDE5APDE4BGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192588-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2023-06-14 | — | — | EP | disclosed |
| EP-4192822-A1 | PYRIDINONE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2023-06-14 | — | — | EP | disclosed |