Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587363 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL20278401 | 0.92 | ALDH1A1 (0.53) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL8404544 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL31186675 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL3344562 | 0.81 | CASP6 (0.62) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| Hydrochloric Acid SCHEMBL21591916 | 0.79 | CASP6 (0.61) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL1163802 | 0.77 | HTT (0.53) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL22324148 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL28370443 | 0.77 | CASP6 (0.62) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB | |
| SCHEMBL30540041 | 0.77 | HTT (0.53) | ALDH1A1HTTCYP1A2CYP2C19PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | CHRM5, CHRM1, CHRM2 | ALDH1A1 622/4885HTT 2614/4885CYP1A2 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.