SCHEMBL8404544

SCHEMBL8404544

Cc1cc2cccnc2cc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
PDGFRB P09619 1/20 0.57
PDGFRA P16234 1/20 0.57
NPC1 O15118 3/20 0.54
POLB P06746 1/20 0.54
RAB9A P51151 1/20 0.54
KDM4E B2RXH2 2/20 0.52
CCR1 P32246 1/20 0.52
CCR8 P51685 1/20 0.52
CASP1 P29466 2/20 0.50
HTT P42858 2/20 0.50
MEN1 O00255 1/20 0.50
CASP7 P55210 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
NR4A2 P43354 1/20 0.50
CASP6 P55212 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186675 1.00 ALDH1A1 (0.61) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL3587114 0.84 CASP6 (0.62) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL5542738 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL3344562 0.84 CASP6 (0.62) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL246244 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL23596020 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL20278401 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL5545370 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL5542743 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL3587363 0.84 ALDH1A1 (0.53) ALDH1A1PDGFRBPDGFRANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230203048-A1 SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-06-29 US disclosed
US-20230203048-A1 SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-06-29 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
EP-3656769-B1 ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) 2023-01-25 EP disclosed
US-20220144829-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. 2022-05-12 US disclosed
WO-2022081925-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2022-04-21 WO disclosed
US-7667228-B2 Metal complex compound and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2010-02-23 US disclosed
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 US disclosed
US-20090192154-A1 SULTAM DERIVATIVES ASAHI KASEI PHARMA CORPORATION (JP) 2009-07-30 US disclosed
US-20090066223-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-12 US disclosed
US-20090069363-A1 Therapeutic Agent for Constipation SHIONOGI & CO. LTD. A LEGAL ENTITY OF JAPAN (JP) 2009-03-12 US disclosed
EP-1857521-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR Mitsubishi Chemical Corporation (JP) 2007-11-21 EP disclosed
US-5283335-A Controlling (mono or di)cotyledenous plants AMERICAN CYANAMID COMPANY (US) 1994-02-01 US disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
US-4515888-A BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-07 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220144829-A1 AMINO ACID COMPOUNDS AND METHODS OF USE ITGB6, ITGA1, ITGAL ALDH1A1 1981/4885PDGFRB 334/4885PDGFRA 483/4885
US-20090069363-A1 Therapeutic Agent for Constipation OPRD1, OPRM1, OPRL1 ALDH1A1 2320/4885PDGFRB 746/4885PDGFRA 1072/4885
US-20230203048-A1 SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, ACE2, PKD1 ALDH1A1 319/4885PDGFRB 1993/4885PDGFRA 1627/4885
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 ALDH1A1 4344/4885PDGFRB 3930/4885PDGFRA 3463/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS ALDH1A1 2839/4885PDGFRB 4136/4885PDGFRA 2690/4885
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 ALDH1A1 180/4885PDGFRB 2224/4885PDGFRA 1994/4885
US-20090192154-A1 SULTAM DERIVATIVES SULT1A1, SULT2A1, ADAMTS1 ALDH1A1 187/4885PDGFRB 2463/4885PDGFRA 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.