Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 6/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25704194 | 1.00 | CFD (0.50) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL4600237 | 0.84 | LMNA (0.60) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL2769498 | 0.84 | CFD (0.67) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL25704193 | 0.83 | NR1I2 (0.40) | KDM4EIDO1NR1I2CYP2C8KMT2A | |
| SCHEMBL30456588 | 0.83 | NR1I2 (0.40) | KDM4EIDO1NR1I2CYP2C8KMT2A | |
| SCHEMBL22319386 | 0.81 | NR4A2 (0.55) | KDM4EMCL1LMNAKMT2AACLY | |
| SCHEMBL11692501 | 0.81 | CFD (0.56) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL12325928 | 0.80 | CFD (0.54) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL25422113 | 0.80 | SLC6A3 (0.48) | CFDKDM4EAPAF1RECQLCASP6 | |
| SCHEMBL4602511 | 0.79 | CFD (0.50) | CFDKDM4EAPAF1RECQLCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448508-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118647606-A | Benzothiophene derivatives as RXFP1 agonists | 百时美施贵宝公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |