Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.50 |
| ▸ | KCNN3 | Q9UGI6 | 6/20 | 0.47 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.47 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564413 | 0.78 | KCNN3 (0.40) | CDK2KCNN3KCNN1KCNN2 | |
| SCHEMBL13117302 | 0.76 | KCNN3 (0.80) | CDK2KCNN3KCNN1KCNN2CCNE1 | |
| SCHEMBL20484514 | 0.75 | DGAT1 (0.36) | KCNN3KCNN1KCNN2 | |
| SCHEMBL7447428 | 0.73 | CYP1A2 (0.44) | CDK2KCNN3KCNN1KCNN2KDM4E | |
| SCHEMBL5452857 | 0.72 | CDK2 (0.65) | CDK2KCNN3KCNN1KCNN2CDK1 | |
| SCHEMBL4878728 | 0.72 | PIK3CD (0.38) | KCNN3KCNN1KCNN2 | |
| SCHEMBL5454018 | 0.70 | CDK2 (0.67) | CDK2KCNN3KCNN1KCNN2CDK1 | |
| SCHEMBL7433874 | 0.70 | KCNN3 (0.41) | CDK2KCNN3KCNN1KCNN2CCNE1 | |
| SCHEMBL25379159 | 0.69 | CDK2 (0.45) | CDK2KCNN3KCNN1KCNN2CDK1 | |
| SCHEMBL12953673 | 0.69 | CDK2 (0.70) | CDK2KCNN3KCNN1KCNN2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |