Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51488 | 1.00 | GRM2 (0.47) | GRM2GAAL3MBTL1IDO1NAMPT | |
| SCHEMBL507617 | 0.89 | GRM2 (0.47) | GRM2GAAL3MBTL1NAMPTCA1 | |
| SCHEMBL24999627 | 0.87 | GRM2 (0.49) | GRM2GAAL3MBTL1NAMPTKDM4A | |
| SCHEMBL29769069 | 0.87 | GRM2 (0.49) | GRM2GAAL3MBTL1NAMPTKDM4A | |
| SCHEMBL17823099 | 0.86 | CA2 (0.49) | IDO1NAMPTCA1CA2AAK1 | |
| SCHEMBL31142951 | 0.86 | ALDH1A1 (0.48) | GRM2GAAL3MBTL1NAMPTCA1 | |
| SCHEMBL3688009 | 0.84 | HDAC1 (0.48) | GRM2GAAL3MBTL1NAMPTCA1 | |
| SCHEMBL1985433 | 0.84 | HDAC1 (0.51) | GRM2GAAL3MBTL1NAMPTCA1 | |
| SCHEMBL16020300 | 0.84 | MMP13 (0.54) | GRM2GAAL3MBTL1NAMPTKDM4A | |
| SCHEMBL31142856 | 0.84 | NOTUM (0.48) | GRM2GAAL3MBTL1NAMPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448508-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |