Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15456384 | 1.00 | ERN1 (0.36) | ERN1HSD17B10KMT2AMEN1TNKS | |
| SCHEMBL13208208 | 0.84 | HSD17B10 (0.38) | ERN1HSD17B10KMT2AALDH1A1AHR | |
| SCHEMBL15459360 | 0.82 | HSD11B1 (0.40) | AHRHSD11B1 | |
| SCHEMBL19137556 | 0.81 | AHR (0.38) | ERN1HSD17B10KMT2AALDH1A1AHR | |
| SCHEMBL16024474 | 0.80 | GABRA1 (0.43) | HSD17B10 | |
| SCHEMBL5950550 | 0.79 | MEN1 (0.44) | HSD17B10KMT2AMEN1TNKSPARP1 | |
| SCHEMBL2646961 | 0.79 | TSHR (0.44) | HSD17B10KMT2AMEN1TNKSPARP1 | |
| SCHEMBL15459309 | 0.78 | ERN1 (0.38) | ERN1ALDH1A1 | |
| SCHEMBL15459066 | 0.78 | AHR (0.36) | ERN1HSD17B10AHR | |
| SCHEMBL15459373 | 0.78 | AHR (0.36) | ERN1HSD17B10ALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |