Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896124 | 1.00 | MAPT (0.49) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL4938844 | 0.82 | MAPT (0.47) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL19243059 | 0.81 | MAOA (0.50) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL8546960 | 0.81 | TTR (0.53) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL2317083 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL30758635 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL11224876 | 0.80 | TTR (0.56) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL4294454 | 0.80 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL4233381 | 0.80 | TTR (0.50) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL2075852 | 0.80 | TTR (0.67) | MAPTKMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736178-B | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117736178-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117510468-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117466868-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-110914241-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |