Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839158 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL18304466 | 0.81 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL4298894 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKMT2ATTR | |
| SCHEMBL30644948 | 0.80 | TTR (0.50) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2075852 | 0.80 | TTR (0.67) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL4233381 | 0.80 | TTR (0.50) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL30458091 | 0.80 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL5896124 | 0.80 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2537253 | 0.80 | MAOA (0.51) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL6849018 | 0.80 | SRC (0.60) | ALDH1A1MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | BONFANTI JEAN-FRANCOIS | 2009-09-03 | — | — | US | disclosed |
| EP-1937272-A2 | BENZODIAZEPINES AS HCV INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007026024-A2 | BENZODIAZEPINES AS HCV INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-03-08 | — | — | WO | disclosed |
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| US-4242357-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4212829-A | Preparation of m-(p-bromophenoxy)benzaldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-07-15 | — | — | US | disclosed |
| EP-0003427-A1 | Preparation of m-(p-bromophenoxy)benzaldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | ALDH1A1 1071/4885MAPT 3042/4885LMNA 4603/4885 |
| US-20090221559-A1 | BENZODIAZEPINES AS HCV INHIBITORS | GABRA5, GABRA4, GABRA3 | ALDH1A1 372/4885MAPT 1578/4885LMNA 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.