Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570209 | 1.00 | SLC6A2 (0.35) | SLC6A2SLC6A4FFAR4SOS1NOS3 | |
| SCHEMBL20570689 | 0.84 | FFAR4 (0.41) | FFAR4MGLL | |
| SCHEMBL20571082 | 0.83 | MGLL (0.40) | FFAR4MGLL | |
| SCHEMBL20571126 | 0.81 | GPR119 (0.41) | FFAR4MGLL | |
| SCHEMBL20570789 | 0.73 | MGLL (0.45) | MGLL | |
| SCHEMBL20571352 | 0.69 | SLC6A2 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL20769542 | 0.69 | MGLL (0.53) | FFAR4MGLL | |
| SCHEMBL20920354 | 0.69 | MGLL (0.48) | MGLL | |
| SCHEMBL28200821 | 0.66 | CHRM3 (0.41) | FFAR4SOS1 | |
| SCHEMBL22350793 | 0.65 | PDE3B (0.42) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |