Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 6/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571082 | 0.91 | MGLL (0.40) | FFAR4MGLLNOTUMCYP2C9FAAH | |
| SCHEMBL20571126 | 0.89 | GPR119 (0.41) | FFAR4MGLL | |
| SCHEMBL20570209 | 0.84 | SLC6A2 (0.35) | FFAR4MGLL | |
| SCHEMBL30458111 | 0.84 | SLC6A2 (0.35) | FFAR4MGLL | |
| SCHEMBL20570789 | 0.80 | MGLL (0.45) | MGLLFAAH | |
| SCHEMBL20567269 | 0.76 | MGLL (0.59) | MGLLFAAH | |
| SCHEMBL20920515 | 0.74 | MGLL (0.49) | MGLLFAAH | |
| SCHEMBL20571807 | 0.74 | MGLL (0.36) | FFAR4MGLLNOTUM | |
| SCHEMBL20569877 | 0.74 | TACR1 (0.42) | MGLL | |
| SCHEMBL30458402 | 0.74 | TACR1 (0.42) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634404-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018217809-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |