Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30458168 | 0.90 | L3MBTL1 (0.47) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL29228913 | 0.89 | HTR6 (0.55) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL30458192 | 0.89 | HTR6 (0.55) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL17109096 | 0.86 | HTR6 (0.55) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL16727070 | 0.86 | HTR6 (0.55) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL16727058 | 0.85 | HTR6 (0.52) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL16727068 | 0.85 | HTR6 (0.54) | HTR6L3MBTL1AKR1C3EPHX1ACHE | |
| SCHEMBL3220344 | 0.84 | L3MBTL1 (0.56) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 | |
| SCHEMBL16727064 | 0.84 | AKR1C3 (0.56) | HTR6L3MBTL1AKR1C3AKR1C2PDE10A | |
| SCHEMBL14499879 | 0.83 | HTR6 (0.55) | HTR6L3MBTL1AKR1C3AKR1C2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408845-A1 | NOVEL COMPOUNDS | Sitryx Therapeutics Limited (GB) | 2024-08-07 | — | — | EP | disclosed |
| CN-118139864-A | New compounds | 西特瑞治疗有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023052783-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-04-06 | — | — | WO | disclosed |