SCHEMBL30458217

SCHEMBL30458217

Cc1cccc(-c2ncccc2[Ir+2])c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 6/20 0.45
BCHE P06276 2/20 0.45
ACHE P22303 1/20 0.45
GRM5 P41594 1/20 0.43
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ADORA1 P30542 1/20 0.42
NPY5R Q15761 1/20 0.41
TGFBR1 P36897 2/20 0.40
NISCH Q9Y2I1 1/20 0.40
TGFBR2 P37173 1/20 0.40
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066076 0.81 CYP2A6 (0.59) MAPK14BCHEACHEGRM5RAB9A
SCHEMBL1370255 0.81 MAPK14 (0.53) MAPK14BCHEACHENPC1HPGD
SCHEMBL31664395 0.79 SYK (0.51) NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL15638862 0.79 RORB (0.46) MAPK14BCHEACHEGRM5NPY5R
SCHEMBL2187789 0.77 ADORA1 (0.55) BCHEACHEGRM5NPC1HPGD
SCHEMBL17487246 0.76 MAPK14 (0.43) MAPK14BCHEACHEGRM5NPY5R
SCHEMBL10094461 0.76 MAPK14 (0.43) MAPK14BCHEACHEGRM5RAB9A
SCHEMBL7949835 0.76 MAPK14 (0.49) MAPK14BCHEACHENPC1HPGD
SCHEMBL16276485 0.73 MAPK14 (0.41) MAPK14BCHEACHENPY5RTGFBR1
SCHEMBL7423732 0.73 KDM4E (0.61) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303011-B Organic compound, light emitting diode having the same, and light emitting device 乐金显示有限公司 2023-06-16 CN disclosed