SCHEMBL2187789

SCHEMBL2187789

Cc1cccc(-c2cccnc2-c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.55
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
FEN1 P39748 1/20 0.46
BCHE P06276 2/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 2/20 0.44
ACHE P22303 1/20 0.44
MAPT P10636 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TGFBR1 P36897 2/20 0.43
PDE10A Q9Y233 1/20 0.43
KMT2A Q03164 1/20 0.43
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27927791 0.88 PTGS2 (0.54) ADORA1PTGS1PTGS2FEN1BCHE
SCHEMBL28059253 0.82 PTGS2 (0.64) ADORA1PTGS1PTGS2FEN1BCHE
SCHEMBL15639333 0.82 TGFBR1 (0.64) ADORA1PTGS1PTGS2BCHEALDH1A1
SCHEMBL30117529 0.82 TGFBR1 (0.64) ADORA1PTGS1PTGS2BCHEALDH1A1
SCHEMBL37278 0.81 PTGS2 (0.66) ADORA1PTGS1PTGS2FEN1HPGD
SCHEMBL15638336 0.81 NPC1 (0.47) PTGS1PTGS2FEN1BCHENPC1
SCHEMBL24716183 0.81 MAPK14 (0.41) ADORA1PTGS1PTGS2BCHEACHE
SCHEMBL15638853 0.81 ALDH1A1 (0.55) BCHENPC1RAB9AALDH1A1ACHE
SCHEMBL13036067 0.80 BCHE (0.47) ADORA1BCHERAB9AACHETGFBR1
Ammonia Solution, Strong SCHEMBL20599554 0.79 PTGS2 (0.64) ADORA1PTGS1PTGS2FEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-11482685-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-10892426-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-12 US disclosed
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-14 US disclosed
US-10593896-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-17 US disclosed
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-16 US disclosed
US-9630983-B2 Organic electroluminescent material and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-04-25 US disclosed
CN-103864675-B Phosphorescent material 通用显示公司 2016-08-31 CN disclosed
US-20150307535-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2015-10-29 US disclosed
US-9076973-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2015-07-07 US disclosed
US-20140021449-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2014-01-23 US disclosed
US-8519384-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-08-27 US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 US disclosed
EP-2342305-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-07-13 EP disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, LMNB2, RUVBL2 ADORA1 4623/4885PTGS1 4701/4885PTGS2 3090/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM ADORA1 2023/4885PTGS1 4010/4885PTGS2 3406/4885
US-10892426-B2 Organic electroluminescent materials and devices OCIAD2, LMNB2, RUVBL2 ADORA1 4623/4885PTGS1 4701/4885PTGS2 3090/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 ADORA1 2121/4885PTGS1 4006/4885PTGS2 3255/4885
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 ADORA1 3447/4885PTGS1 3959/4885PTGS2 3309/4885
US-20110227049-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 ADORA1 1654/4885PTGS1 4266/4885PTGS2 3955/4885
US-11482685-B2 Organic electroluminescent materials and devices EML4, MCM4, KCNMB4 ADORA1 2121/4885PTGS1 4006/4885PTGS2 3255/4885
US-10593896-B2 Organic electroluminescent materials and devices TYR, DDT, EML4 ADORA1 3447/4885PTGS1 3959/4885PTGS2 3309/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM ADORA1 2023/4885PTGS1 4010/4885PTGS2 3406/4885
US-20150307535-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 ADORA1 1654/4885PTGS1 4266/4885PTGS2 3955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.