Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.46 |
| ▸ | TNK1 | Q13470 | 4/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 6/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790468 | 0.82 | HTR2C (0.51) | PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL30459017 | 0.82 | HTR2C (0.46) | PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL25420240 | 0.82 | PARP1 (0.39) | PARP1TNK1TNK2PANK3VEGFA | |
| SCHEMBL30458906 | 0.81 | VEGFA (0.41) | PARP1TNK1TNK2HTR2AHTR2C | |
| SCHEMBL31076539 | 0.80 | IKZF2 (0.55) | — | |
| SCHEMBL25647384 | 0.80 | IKZF2 (0.55) | — | |
| SCHEMBL30459674 | 0.79 | HTR2B (0.39) | PARP1TNK1TNK2HTR2AHTR2C | |
| SCHEMBL30790625 | 0.77 | CRBN (0.47) | PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL30459129 | 0.77 | HTR2B (0.44) | PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL30458379 | 0.77 | HTR2B (0.44) | PARP1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |