SCHEMBL30459618

SCHEMBL30459618

O=C1N=Cc2cc(CO)cc(F)c21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
CASP6 P55212 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28983718 0.73
SCHEMBL29960521 0.73
SCHEMBL20300390 0.68 CHEK1 (0.38)
SCHEMBL30503673 0.68 CHEK1 (0.38)
SCHEMBL33377367 0.64 CA1 (0.36)
SCHEMBL29024953 0.64 CA12 (0.35)
SCHEMBL2642236 0.64 ACHE (0.42) KDM4ECASP6
SCHEMBL391375 0.63 ACHE (0.46) KDM4ECASP6
SCHEMBL28983785 0.62
SCHEMBL16080734 0.62 KIF11 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104155-A1 LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF 标新生物医药科技(上海)有限公司 2023-06-15 WO disclosed