SCHEMBL391375

SCHEMBL391375

OCc1cc(F)c(F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
KIF11 P52732 1/20 0.36
P2RX7 Q99572 2/20 0.36
MAOB P27338 1/20 0.36
RIPK1 Q13546 1/20 0.36
TSHR P16473 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CASP6 P55212 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16080734 0.86 KIF11 (0.38) ACHECES2CES1CYP4F2CYP4A11
SCHEMBL31338769 0.83 ACHE (0.37) ACHECES2CES1CYP4F2CYP4A11
SCHEMBL29738548 0.83 ACHE (0.37) ACHECES2CES1CYP4F2CYP4A11
SCHEMBL15823224 0.83 ACHE (0.37) ACHECYP4F2CYP4A11KIF11P2RX7
SCHEMBL15814084 0.83 ACHE (0.37) ACHECES2CES1CYP4F2CYP4A11
SCHEMBL2642238 0.80 ACHE (0.50) ACHECYP4F2CYP4A11KIF11TSHR
SCHEMBL523766 0.80 ACHE (0.43) ACHECYP4F2CYP4A11KIF11TSHR
SCHEMBL24852184 0.79 KIF11 (0.49) ACHECYP4F2CYP4A11KIF11RIPK1
SCHEMBL29738504 0.79 KIF11 (0.49) ACHECYP4F2CYP4A11KIF11RIPK1
SCHEMBL1239272 0.79 CES2 (0.38) CES2CES1MAOBRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113559904-B Application of nitrogen-carbon material anchored iron single-atom catalyst in catalyzing ammoxidation of alcohol to prepare nitrile 南京理工大学 2024-04-02 CN claimed
CN-112341546-B Preparation method of fluorinated biomass membrane material 北京化工大学 2022-07-05 CN claimed
CN-113559904-A Application of nitrogen-carbon material anchored iron monatomic catalyst in reaction for catalyzing ammoxidation of alcohol to prepare nitrile 南京理工大学 2021-10-29 CN claimed
CN-112341546-A Preparation method of fluorinated biomass membrane material 北京化工大学 2021-02-09 CN claimed
CN-111253415-A Norcantharidin carboxylic acid trifluorobenzyl ester and synthetic method and application thereof 遵义医科大学 2020-06-09 CN claimed
CN-108976354-A A kind of environmentally friendly type polyurethane complex thickener and preparation method thereof of associating 黄山泰尔新材料有限公司 2018-12-11 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
WO-2010002175-A2 RESIN COMPOSITION FOR CLADDING OF OPTICAL FIBER SSCP CO., LTD. (KR) 2010-01-07 WO claimed
US-20260109674-A1 ALLOSTERIC MODULATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR EFFICACY THE UNIVERSITY OF TOLEDO (US) 2026-04-23 US disclosed
EP-4174070-B1 TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF NEUSCO BIOTECH LTD (CN) 2025-10-29 EP disclosed
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS INC (US) 2025-10-02 US disclosed
EP-4263749-B1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2025-06-18 EP disclosed
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-119161343-A Bridged pyrimidinone compounds, preparation method thereof, pharmaceutical composition and application thereof 上海深势唯思科技有限责任公司 2024-12-20 CN disclosed
JP-2006001925-A METHOD FOR PRODUCING 3,4,5-TRIFLUOROBENZYL ALCOHOL SHOWA DENKO KK 2006-01-05 JP disclosed
WO-2005113582-A1 SUBSTITUTED ETHANE-1,2-DIAMINES FOR THE TREATMENT OF ALZHEIMER'S DISEASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-12-01 WO disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed
US-6452056-B1 REDUCING FLUORINATED BENZONITRILE TO A BENZYLAMINE WHICH IS REPLACED WITH A HYDROXYL GROUP ASAHI GLASS COMPANY, LIMITED (JP) 2002-09-17 US disclosed
EP-1114809-A1 PROCESS FOR THE PREPARATION OF FLUOROBENZYL DERIVATIVES Asahi Glass Co., Ltd. (JP) 2001-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 ACHE 1187/4885CES2 35/4885CES1 224/4885
US-20260109674-A1 ALLOSTERIC MODULATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR EFFICACY CHRM5, CHRM3, CHRNA3 ACHE 51/4885CES2 2321/4885CES1 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.