Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.30 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459684 | 0.84 | MEN1 (0.36) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL30267386 | 0.81 | ESR1 (0.31) | CYP3A4 | |
| SCHEMBL12505515 | 0.71 | INSR (0.36) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL25364854 | 0.71 | FAAH (0.33) | — | |
| SCHEMBL29522410 | 0.69 | MEN1 (0.40) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL30267316 | 0.69 | KDM5C (0.31) | ALDH1A1MAPT | |
| SCHEMBL1425947 | 0.68 | CHRNB2 (0.41) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL27322521 | 0.68 | MEN1 (0.33) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL16423522 | 0.66 | KHK (0.44) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29475977 | 0.66 | FAAH (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |