Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215266 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL7102411 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| SCHEMBL188578 | 0.79 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL26923027 | 0.79 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL31168037 | 0.78 | SOD1 (0.39) | — | |
| SCHEMBL30702019 | 0.78 | BACE1 (0.39) | — | |
| SCHEMBL27191843 | 0.78 | BACE1 (0.39) | — | |
| SCHEMBL27978363 | 0.78 | CYP1A1 (0.41) | — | |
| SCHEMBL27978105 | 0.78 | CYP11B1 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL15034034 | 0.78 | CHRNB1 (0.43) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457346-A | Preparation of indolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-07-18 | — | — | CN | disclosed |