Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.39 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30308375 | 1.00 | LTA4H (0.56) | LTA4HHIF1AEPAS1GRM2ALDH1A1 | |
| SCHEMBL14960477 | 0.86 | LTA4H (0.57) | LTA4HGRM2ALDH1A1PDE1BHRH3 | |
| SCHEMBL12214 | 0.86 | LTA4H (0.57) | LTA4HGRM2ALDH1A1PDE1BHRH3 | |
| SCHEMBL30508309 | 0.84 | LTA4H (0.56) | LTA4HGRM2ALDH1A1PDE1BHRH3 | |
| SCHEMBL8805178 | 0.84 | LTA4H (0.56) | LTA4HGRM2ALDH1A1PDE1BHRH3 | |
| SCHEMBL1005882 | 0.84 | LTA4H (0.62) | LTA4HCNR2PIK3CDPIK3R2PIK3CA | |
| SCHEMBL1189298 | 0.84 | LTA4H (0.62) | LTA4HCNR2PIK3CDPIK3R2PIK3CA | |
| SCHEMBL1005883 | 0.84 | LTA4H (0.62) | LTA4HCNR2PIK3CDPIK3R2PIK3CA | |
| SCHEMBL22011076 | 0.82 | LTA4H (0.54) | LTA4HGRM2ALDH1A1PDE1BHRH3 | |
| SCHEMBL3509984 | 0.82 | SMN1; SMN2 (0.59) | LTA4HALDH1A1PDE1BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754685-B | Dihydrothiochromene pyrazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |