Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960606 | 0.86 | MAOB (0.54) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL29993564 | 0.86 | MAOB (0.54) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL15867533 | 0.86 | CYP19A1 (0.51) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL21735349 | 0.81 | SHBG (0.61) | CYP3A4CYP1A2KDM4EKMT2ACYP1A1 | |
| SCHEMBL21295874 | 0.80 | CYP2A6 (0.42) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL21735530 | 0.79 | CYP19A1 (0.62) | CYP3A4CYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL21295722 | 0.76 | CYP2A6 (0.42) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL25218648 | 0.74 | KDM4E (0.42) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL30461684 | 0.74 | KDM4E (0.42) | CYP2A6CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL21476417 | 0.73 | MAOB (0.50) | CYP2A6ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444721-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |