Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803108 | 0.82 | CYP19A1 (0.52) | CYP19A1CYP11B2CYP11B1CYP17A1APP | |
| SCHEMBL11803103 | 0.82 | CYP19A1 (0.52) | CYP19A1CYP11B2CYP11B1CYP17A1APP | |
| SCHEMBL10899813 | 0.82 | APP (0.57) | APPKDM4ENPC1RAB9ACYP3A4 | |
| SCHEMBL6822627 | 0.82 | NPC1 (0.66) | CYP19A1APPKDM4EMEN1KMT2A | |
| SCHEMBL15867533 | 0.81 | CYP19A1 (0.51) | CYP19A1CYP11B2CYP11B1CYP17A1KDM4E | |
| SCHEMBL21735349 | 0.79 | SHBG (0.61) | CYP19A1CYP11B2CYP11B1CYP17A1APP | |
| SCHEMBL30461597 | 0.79 | CYP2A6 (0.47) | CYP19A1CYP11B2CYP11B1CYP17A1KDM4E | |
| SCHEMBL29993564 | 0.79 | MAOB (0.54) | CYP19A1CYP11B2CYP11B1CYP17A1KDM4E | |
| SCHEMBL2960606 | 0.79 | MAOB (0.54) | CYP19A1CYP11B2CYP11B1CYP17A1KDM4E | |
| SCHEMBL6748778 | 0.78 | APP (0.64) | APPKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | CYP19A1 2317/4885CYP11B2 2816/4885CYP11B1 2888/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | CYP19A1 2317/4885CYP11B2 2816/4885CYP11B1 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.