Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627792 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 | |
| SCHEMBL14556227 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 | |
| SCHEMBL28276692 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 | |
| SCHEMBL6623163 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 | |
| SCHEMBL20284348 | 0.81 | STK17B (0.40) | ALDH1A1SMN1; SMN2KDM4EPIN1KMT2A | |
| SCHEMBL30462029 | 0.79 | KDM4E (0.40) | ALDH1A1SMN1; SMN2KDM4EPIN1KMT2A | |
| SCHEMBL26627800 | 0.79 | KDM4E (0.40) | ALDH1A1SMN1; SMN2KDM4EPIN1KMT2A | |
| SCHEMBL1442231 | 0.79 | TRPM8 (0.54) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 | |
| SCHEMBL1442559 | 0.79 | PGK1 (0.51) | ALDH1A1SMN1; SMN2KDM4EPGK1STK17A | |
| SCHEMBL31368659 | 0.79 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4EPIN1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |