Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.59 |
| ▸ | AR | P10275 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934288 | 0.84 | MEN1 (0.70) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL3934282 | 0.84 | MEN1 (0.70) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL3939910 | 0.84 | PGR (0.67) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL3939914 | 0.84 | PGR (0.67) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL10868391 | 0.81 | LMNA (0.72) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL1650395 | 0.81 | LMNA (0.72) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL144436 | 0.81 | LMNA (0.72) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL8642981 | 0.81 | CYP19A1 (0.70) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL11789347 | 0.81 | CYP19A1 (0.70) | PGRARCYP3A4CHRM1ALDH1A1 | |
| SCHEMBL11788230 | 0.81 | PGR (0.63) | PGRARCYP3A4CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100028360-A1 | METHODS FOR THE MODULATION OF BRAIN PROGESTAGEN SIGNALING IN THE PREVENTION AND TREATMENT OF NEUROLOGICAL DISORDERS AND NEURODEGENERATIVE DISEASES | ATWOOD CRAIG STEPHEN | 2010-02-04 | — | — | US | disclosed |