Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19470000 | 0.85 | OPRM1 (0.44) | OPRM1ALDH1A1CYP2D6NPC1RAB9A | |
| SCHEMBL28325581 | 0.81 | TDP1 (0.44) | OPRM1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4201868 | 0.78 | MEN1 (0.50) | OPRM1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL5592055 | 0.77 | NPSR1 (0.41) | OPRM1CYP2D6NPC1RAB9ANPSR1 | |
| SCHEMBL3887512 | 0.77 | AKT1 (0.39) | OPRM1L3MBTL1NPSR1 | |
| SCHEMBL6790349 | 0.72 | SMN1; SMN2 (0.52) | OPRM1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL31164812 | 0.70 | NPC1 (0.61) | MAPK1NPC1RAB9ASMN1; SMN2ATM | |
| SCHEMBL11670899 | 0.69 | L3MBTL1 (0.53) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8060186 | 0.69 | SRD5A1 (0.54) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28285338 | 0.69 | OPRM1 (0.40) | OPRM1ALDH1A1CYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |