Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225233 | 1.00 | FAAH (0.45) | FAAHCES1KMT2AMAOAMAOB | |
| SCHEMBL3767625 | 0.72 | QPCT (0.54) | FAAHCES1KMT2AQPCTQPCTL | |
| SCHEMBL25156831 | 0.72 | JAK2 (0.52) | KMT2AMAOAMAOBADRA2AGRM4 | |
| SCHEMBL30961329 | 0.72 | FAAH (0.46) | FAAHCES1QPCTQPCTLMETAP2 | |
| SCHEMBL3985729 | 0.71 | AHR (0.59) | KMT2AMAOAMAOBCYP1A1CYP1B1 | |
| SCHEMBL5061307 | 0.71 | MAOB (0.49) | KMT2AMAOAMAOBF2RL3PDE4D | |
| SCHEMBL11281487 | 0.70 | METAP2 (0.48) | KMT2AF2RL3METAP2GRM4CNR2 | |
| SCHEMBL13049682 | 0.70 | FAAH (0.44) | FAAHCES1KMT2AQPCTQPCTL | |
| SCHEMBL3564444 | 0.70 | QPCT (0.45) | FAAHCES1KMT2AQPCTQPCTL | |
| SCHEMBL1116268 | 0.69 | ALDH1A1 (0.43) | FAAHCES1KMT2AQPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |