Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CD38 | P28907 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020749 | 0.83 | PIK3CD (0.50) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL14320606 | 0.76 | APP (0.50) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL30463551 | 0.75 | DYRK1A (0.47) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL18927620 | 0.74 | MAPT (0.44) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL20950907 | 0.74 | TEK (0.43) | CHEK1CHEK2DYRK1ACD38 | |
| SCHEMBL571374 | 0.72 | HDAC8 (0.50) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL13745367 | 0.72 | DYRK1A (0.46) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL14757630 | 0.72 | DHFR (0.44) | CHEK1CHEK2IMPDH2 | |
| SCHEMBL17701204 | 0.71 | DYRK1A (0.41) | CHEK1CHEK2MAPTDYRK1ACD38 | |
| SCHEMBL4859450 | 0.69 | MAP4K4 (0.56) | MAPTALOX5APLMNAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |