SCHEMBL30463742

SCHEMBL30463742

CC(C)N(CCC(=O)NNC(=O)c1ccccc1Nc1ccc(C(F)(F)F)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 11/20 0.42
▸ PSMB5 P28074 1/20 0.38
▸ ABCG2 Q9UNQ0 1/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ KCNA5 P22460 1/20 0.35
▸ PPARG P37231 1/20 0.35
▸ PPARD Q03181 1/20 0.35
▸ PPARA Q07869 1/20 0.35
▸ NR1H4 Q96RI1 1/20 0.35
▸ TAS2R14 Q9NYV8 2/20 0.35
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22571364 1.00 RXFP1 (0.42) RXFP1PSMB5ABCG2MAPK8KCNA5
SCHEMBL22571359 0.92 PSMB5 (0.43) RXFP1PSMB5ABCG2MAPK8KCNA5
SCHEMBL30463790 0.92 PSMB5 (0.43) RXFP1PSMB5ABCG2MAPK8KCNA5
SCHEMBL22556345 0.89 RXFP1 (0.43) RXFP1ABCG2MAPK8PPARGPPARD
SCHEMBL23701588 0.89 RXFP1 (0.44) RXFP1PSMB5ABCG2MAPK8KCNA5
SCHEMBL22571446 0.87 RXFP1 (0.44) RXFP1ABCG2MAPK8PPARGPPARD
SCHEMBL30463783 0.87 RXFP1 (0.44) RXFP1ABCG2MAPK8PPARGPPARD
SCHEMBL22556350 0.86 TRPV4 (0.43) RXFP1ABCG2MAPK8PPARGPPARD
SCHEMBL22556555 0.84 RXFP1 (0.42) RXFP1ABCG2MAPK8TAS2R14POLB
SCHEMBL22556510 0.83 RXFP1 (0.45) RXFP1ABCG2MAPK8TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11661403-B2 Oxadiazole compounds VIVACE THERAPEUTICS, INC. (US) 2023-05-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661403-B2 Oxadiazole compounds YAP1, TEAD2, TEAD3 RXFP1 3511/4885PSMB5 4204/4885ABCG2 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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