SCHEMBL304670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL890076	0.86	CYP2A13 (0.59)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL755778	0.85	KMT2A (0.55)	CYP2C9CYP2D6PLK1ALDH1A1KMT2A
	SCHEMBL11193326	0.84	CYP2A13 (0.75)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL753109	0.83	KMT2A (0.57)	CYP2C9CYP2D6PLK1ALDH1A1KMT2A
	SCHEMBL10150886	0.83	CYP2A13 (0.56)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL888767	0.83	CYP2A13 (0.56)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL1967517	0.82	POLB (0.59)	CYP2C19PLK1HTTSMN1; SMN2ALDH1A1
	SCHEMBL2627962	0.82	CYP2A13 (0.55)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL8907096	0.82	CYP2A13 (0.55)	CYP2A13CYP2C9CYP3A4CYP2D6CYP2C19
	SCHEMBL14828680	0.81	LMNA (0.55)	ALOX15ALDH1A1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.