Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.39 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040539 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL27944723 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL29897548 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL2294654 | 0.78 | CYP2C19 (0.48) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL10436625 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL3039574 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL4507384 | 0.72 | CA2 (0.42) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL2436993 | 0.72 | GLRA3 (0.65) | SMN1; SMN2ALDH1A1CA2TYRPOLB | |
| SCHEMBL8374077 | 0.71 | CA1 (0.46) | ALDH1A1CA2CA1ALOX15HIF1A | |
| SCHEMBL1245154 | 0.70 | CYP2C19 (0.48) | SMN1; SMN2ALDH1A1CA2TYRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574328-B | Economical and practical resolution method of 2,2' -biphenol compound | 广东工业大学 | 2022-12-20 | — | — | CN | claimed |
| CN-111574450-B | Novel chiral biphenyl quaternary ammonium salt phase transfer catalyst and preparation method and application thereof | 广东工业大学 | 2021-10-29 | — | — | CN | claimed |
| CN-111574450-A | Novel chiral biphenyl quaternary ammonium salt phase transfer catalyst and preparation method and application thereof | 广东工业大学 | 2020-08-25 | — | — | CN | claimed |
| CN-111574328-B | Economical and practical resolution method of 2,2' -biphenol compound | 广东工业大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-111574328-B | Economical and practical resolution method of 2,2' -biphenol compound | 广东工业大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-111574450-B | Novel chiral biphenyl quaternary ammonium salt phase transfer catalyst and preparation method and application thereof | 广东工业大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-111574328-A | Economical and practical resolution method of 2,2' -biphenol compound | 广东工业大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-111574450-A | Novel chiral biphenyl quaternary ammonium salt phase transfer catalyst and preparation method and application thereof | 广东工业大学 | 2020-08-25 | — | — | CN | disclosed |
| EP-2241545-B1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND METHOD FOR PRODUCING THE SAME | NIPPON SODA CO (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-8283501-B2 | Optically active 2,2′-biphenol derivative and production method of same | NIPPON SODA CO., LTD. (JP) | 2012-10-09 | — | — | US | disclosed |
| US-20100280284-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND PRODUCTION METHOD OF SAME | NIPPON SODA CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2241545-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND METHOD FOR PRODUCING THE SAME | Nippon Soda Co., Ltd. (JP) | 2010-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280284-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND PRODUCTION METHOD OF SAME | SQLE, CYP2J2, CYP24A1 | SMN1; SMN2 4802/4885ALDH1A1 222/4885CA2 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.