Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469018 | 0.78 | HDAC3 (0.31) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL21518572 | 0.75 | PTGS1 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL30469008 | 0.74 | PTGS1 (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL31087111 | 0.73 | PAOX (0.44) | TPSAB1KDM4EMEN1MAPTPABPC1 | |
| SCHEMBL30469016 | 0.68 | HTR1A (0.30) | CYP2C19 | |
| SCHEMBL19708893 | 0.68 | MAPT (0.36) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL17841861 | 0.67 | GSK3A (0.41) | TSHRPPIDCYP1A2CYP2C19CA1 | |
| SCHEMBL18165064 | 0.67 | HDAC1 (0.41) | TSHRHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL30396758 | 0.66 | PTGS1 (0.53) | TSHRMEN1MAPTKMT2A | |
| SCHEMBL25704170 | 0.65 | ALDH1A1 (0.47) | CYP1A2CYP2C19KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469090-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | Genentech Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |