Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469008 | 0.91 | PTGS1 (0.32) | — | |
| SCHEMBL12301862 | 0.72 | MGLL (0.54) | — | |
| SCHEMBL30831334 | 0.70 | PTGS1 (0.54) | — | |
| SCHEMBL30468997 | 0.68 | TPSAB1 (0.34) | CYP2C19 | |
| SCHEMBL17527857 | 0.67 | MGLL (0.45) | — | |
| SCHEMBL18474152 | 0.66 | MGLL (0.52) | CYP2C19 | |
| SCHEMBL20087403 | 0.65 | PTGS1 (0.47) | CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL25427031 | 0.63 | PTGS1 (0.36) | CYP2C19 | |
| SCHEMBL21766070 | 0.63 | MGLL (0.43) | — | |
| SCHEMBL31087102 | 0.63 | CHRM2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469090-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | Genentech Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |