Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802503 | 1.00 | ADRA2C (0.47) | ADRA2CMAPTALDH1A1CASP1MEN1 | |
| SCHEMBL19690404 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHDAC4SMN1; SMN2 | |
| SCHEMBL14320347 | 0.79 | HDAC4 (0.47) | ADRA2CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31175173 | 0.79 | TSHR (0.55) | ALDH1A1MEN1KMT2AALOX15HDAC4 | |
| SCHEMBL38659130 | 0.78 | ADRB1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12966321 | 0.77 | LRRK2 (0.37) | ALDH1A1HDAC4SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL12802563 | 0.74 | MEN1 (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL38659133 | 0.72 | NPY1R (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6942579 | 0.72 | ADRA2C (0.80) | ADRA2CMAPTALDH1A1CASP1MEN1 | |
| SCHEMBL26185698 | 0.72 | ADRA2C (0.61) | ADRA2CMAPTALDH1A1CASP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |