Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557361 | 1.00 | RXRA (0.54) | RXRARXRBALOX5TSHRLMNA | |
| SCHEMBL7671999 | 0.90 | TSHR (0.55) | TSHRLMNAMAPTMEN1RAB9A | |
| SCHEMBL30469306 | 0.82 | MAOB (0.60) | TSHRLMNAMAPTPLGPLAU | |
| SCHEMBL20557970 | 0.82 | MAOB (0.60) | TSHRLMNAMAPTPLGPLAU | |
| SCHEMBL7275469 | 0.81 | ALOX5 (0.62) | ALOX5TSHRLMNAMAPTRAB9A | |
| SCHEMBL6738366 | 0.79 | TSHR (0.76) | TSHRLMNAMAPTMEN1RAB9A | |
| SCHEMBL3879951 | 0.78 | TSHR (0.52) | TSHRLMNAACHEF2ALDH1A1 | |
| SCHEMBL7873587 | 0.78 | TSHR (0.52) | TSHRLMNAACHEF2ALDH1A1 | |
| SCHEMBL20299326 | 0.78 | TSHR (0.52) | TSHRLMNAACHEF2ALDH1A1 | |
| SCHEMBL27924572 | 0.78 | TSHR (0.52) | TSHRLMNAACHEF2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |