Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722406 | 0.95 | LMNA (0.58) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL303115 | 0.90 | LMNA (0.52) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL1725046 | 0.87 | LMNA (0.54) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL303692 | 0.87 | LMNA (0.66) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL1725647 | 0.86 | LMNA (0.53) | LMNASMN1; SMN2HTTKMT2AGAA | |
| SCHEMBL1711093 | 0.85 | LMNA (0.71) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL3275527 | 0.84 | LMNA (0.51) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL306227 | 0.84 | TSHR (0.49) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL303907 | 0.83 | LMNA (0.65) | LMNASMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL302045 | 0.83 | SLC6A7 (0.53) | LMNASMN1; SMN2HTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | disclosed |