Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755148 | 0.84 | GCK (0.50) | GCKCXCR2POLBMEN1KMT2A | |
| SCHEMBL7095081 | 0.82 | GCK (0.52) | GCKCXCR2POLBNPC1RAB9A | |
| SCHEMBL29018632 | 0.80 | HCAR3 (0.44) | GCKRAB9ADEGS1HCAR3 | |
| SCHEMBL5143604 | 0.79 | DEGS1 (0.65) | GCKPOLBNPC1RAB9ADEGS1 | |
| SCHEMBL7090892 | 0.76 | POLB (0.52) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22607251 | 0.76 | RAB9A (0.59) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23608334 | 0.75 | POLB (0.51) | GCKPOLBNPC1RAB9ADEGS1 | |
| SCHEMBL31307412 | 0.75 | POLB (0.51) | GCKPOLBNPC1RAB9ADEGS1 | |
| SCHEMBL24616597 | 0.75 | SMN1; SMN2 (0.54) | GCKPOLBKMT2ANPC1RAB9A | |
| SCHEMBL18216846 | 0.73 | TRPV1 (0.52) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283994-A | Heterocyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2023-06-23 | — | — | CN | disclosed |