Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.70 |
| ▸ | AR | P10275 | 6/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluocortolone SCHEMBL21706397 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL4644 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL11518086 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL11862489 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL19327147 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL13902941 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL11333890 | 1.00 | PGR (0.70) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL144059 | 0.99 | PGR (0.69) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL21852268 | 0.98 | PGR (0.68) | PGRARADRA1ACHRM1ADORA3 | |
| Fluocortolone SCHEMBL3690986 | 0.97 | PGR (0.67) | PGRARADRA1ACHRM1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181704-B1 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INT AG (CH) | 2015-05-06 | — | — | EP | claimed |
| EP-2181704-A2 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG (CH) | 2010-05-05 | — | — | EP | claimed |
| EP-1594459-B1 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INT AG (CH) | 2010-02-17 | — | — | EP | claimed |
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | EPIGENESIS PHARMACEUTICALS, LLC | 2007-01-25 | — | — | US | claimed |
| EP-1448202-A1 | COMBINATION OF A PDE4 OR PDE3/4 INHIBITOR AND AN ANTI-RHEUMATIC DRUG | ALTANA Pharma AG (DE) | 2004-08-25 | — | — | EP | claimed |
| WO-2003039552-A1 | COMBINATION OF PDE4 OR PDE3/4 INHIBITOR AND AN ANTI-RHEUMATIC DRUG | ALTANA PHARMA AG (DE) | 2003-05-15 | — | — | WO | claimed |
| US-20030092706-A1 | Combination | NYCOMED GMBH (DE) | 2003-05-15 | — | — | US | claimed |
| EP-0374185-B1 | IMPROVED 9$g(a)-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1993-02-10 | — | — | EP | claimed |
| US-4704358-A | Δ1 -dehydrogenation with heat or air-dried B. cyclooxidans | THE UPJOHN COMPANY (US) | 1987-11-03 | — | — | US | claimed |
| US-4524134-A | BIOCONVERSION WITH ARTHROBACTER SIMPLEX | THE UPJOHN COMPANY (US) | 1985-06-18 | — | — | US | claimed |
| US-4011317-A | STEROID DERIVATIVES | RORER ITALIANA S.P.A. (IT) | 1977-03-08 | — | — | US | claimed |
| US-11913031-B2 | Method to reproduce circadian rhythms on a microfluidic chip | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-02-27 | — | — | US | disclosed |
| US-20200318077-A1 | METHOD TO REPRODUCE CIRCADIAN RHYTHMS ON A MICROFLUIDIC CHIP | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-10-08 | — | — | US | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| US-9326934-B2 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG | 2016-05-03 | — | — | US | disclosed |
| US-4170518-A | Microbiological conversion of sterol derivatives to 5-androsten-17-one derivatives and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-10-09 | — | — | US | disclosed |
| US-4017615-A | ESPECIALLY USEFUL FOR ANTIINFLAMMATORY TOPICAL CORTICOIDS | SYNTEX CORPORATION (PM) | 1977-04-12 | — | — | US | disclosed |
| US-3984544-A | Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |
| US-3956347-A | Novel pregnanoic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3935245-A | DIAGNOSTIC | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | RECQL, GSS, DDX17 | PGR 965/4885AR 209/4885ADRA1A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.