Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860730 | 1.00 | PIM1 (0.59) | PIM1PTPN1GSK3AGSK3BPTPN2 | |
| SCHEMBL7867091 | 0.79 | PTPN1 (0.50) | PTPN1PTPN2CDC25BPARP15PARP10 | |
| SCHEMBL29702290 | 0.79 | GSK3A (0.67) | PIM1GSK3AGSK3BALDH1A1CA9 | |
| SCHEMBL8824959 | 0.76 | TDP1 (0.41) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL30990560 | 0.76 | PIM1 (1.00) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL26710431 | 0.75 | GSK3A (0.65) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL8825038 | 0.74 | GSK3A (0.41) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL8875541 | 0.74 | GSK3A (0.55) | PIM1GSK3AGSK3BALDH1A1CA9 | |
| SCHEMBL8877320 | 0.72 | PTPN1 (0.64) | PTPN1PTPN2CDC25BPARP15PARP10 | |
| SCHEMBL8876594 | 0.72 | PTPN1 (0.60) | PTPN1PTPN2CDC25BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210808-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210808-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | PIM1 3612/4885PTPN1 346/4885GSK3A 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.