Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.64 |
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 10/20 | 0.57 |
| ▸ | CDC25B | P30305 | 10/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 6/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937570 | 0.86 | MAOB (0.71) | PTPN1MAOBPARP15PARP10PARP14 | |
| SCHEMBL8876594 | 0.85 | PTPN1 (0.60) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL5397207 | 0.85 | PTPN1 (0.60) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL7239415 | 0.83 | MAOB (0.58) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL8877502 | 0.80 | PARP10 (0.58) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL3231630 | 0.80 | ALOX5 (0.71) | MAOB | |
| SCHEMBL12443168 | 0.79 | PTPN1 (0.53) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL14300059 | 0.78 | PTPN1 (0.71) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| Netoglitazone SCHEMBL142658 | 0.76 | FFAR1 (0.55) | PTPN1PTPN2CDC25BPARP15PARP10 | |
| Netoglitazone SCHEMBL29361540 | 0.76 | FFAR1 (0.55) | PTPN1PTPN2CDC25BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |