Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.48 |
| ▸ | CDC25B | P30305 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860730 | 0.79 | PIM1 (0.59) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL30475601 | 0.79 | PIM1 (0.59) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL8877320 | 0.72 | PTPN1 (0.64) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL8876594 | 0.72 | PTPN1 (0.60) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL5397207 | 0.72 | PTPN1 (0.60) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL10281143 | 0.71 | PTPN1 (0.48) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL305465 | 0.70 | PTPN1 (0.53) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL4239883 | 0.69 | MAOB (0.51) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| SCHEMBL6389087 | 0.69 | PTPN1 (0.49) | PTPN1PTPN2CDC25BMAOBPARP15 | |
| Netoglitazone SCHEMBL142658 | 0.69 | FFAR1 (0.55) | PTPN1PTPN2CDC25BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131310-A1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-12 | — | — | EP | claimed |
| WO-2000031055-A1 | CHRYSTALS OF 5-[{6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL}METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-02 | — | — | WO | claimed |
| EP-1131310-A1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031055-A1 | CHRYSTALS OF 5-[{6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL}METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-02 | — | — | WO | disclosed |