Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475601 | 1.00 | PIM1 (0.59) | PIM1PTPN1GSK3AGSK3BPTPN2 | |
| SCHEMBL7867091 | 0.79 | PTPN1 (0.50) | PTPN1PTPN2CDC25BPARP15PARP10 | |
| SCHEMBL29702290 | 0.79 | GSK3A (0.67) | PIM1GSK3AGSK3BALDH1A1CA9 | |
| SCHEMBL8824959 | 0.76 | TDP1 (0.41) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL30990560 | 0.76 | PIM1 (1.00) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL26710431 | 0.75 | GSK3A (0.65) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL8825038 | 0.74 | GSK3A (0.41) | PIM1GSK3AGSK3BALDH1A1MAOB | |
| SCHEMBL8875541 | 0.74 | GSK3A (0.55) | PIM1GSK3AGSK3BALDH1A1CA9 | |
| SCHEMBL8877320 | 0.72 | PTPN1 (0.64) | PTPN1PTPN2CDC25BPARP15PARP10 | |
| SCHEMBL8876594 | 0.72 | PTPN1 (0.60) | PTPN1PTPN2CDC25BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131310-A1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-12 | — | — | EP | claimed |
| WO-2000031055-A1 | CHRYSTALS OF 5-[{6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL}METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-02 | — | — | WO | claimed |
| US-5753681-A | INSULIN SENSITIZERS | SANKYO COMPANY, LIMITED (JP) | 1998-05-19 | — | — | US | claimed |
| EP-1131310-A1 | CHRYSTALS OF 5- 6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031055-A1 | CHRYSTALS OF 5-[{6-(2-FLUOROBENZYL)OXY-2-NAPHTHYL}METHYL]-2,4-THIAZOLIDINEDIONE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-02 | — | — | WO | disclosed |