Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476276 | 0.80 | HSD11B1 (0.46) | PDK4GPR119PDK2CHRM2CHRM4 | |
| SCHEMBL19341628 | 0.79 | UCHL1 (0.39) | ROCK2PDK4RORCGPR119PDK2 | |
| SCHEMBL17586451 | 0.78 | RORC (0.42) | USP30ROCK2PDK4RORCPDK2 | |
| SCHEMBL30476275 | 0.76 | DHODH (0.34) | — | |
| SCHEMBL30695735 | 0.75 | USP30 (0.47) | USP30ROCK2PDK4GPR119PDK2 | |
| SCHEMBL30334973 | 0.75 | RORC (0.45) | USP30RORCGPR119PDK2HDAC1 | |
| SCHEMBL15156278 | 0.75 | RORC (0.45) | USP30RORCGPR119PDK2HDAC1 | |
| SCHEMBL23291785 | 0.74 | RORC (0.44) | RORCGPR119PDK2HDAC1HDAC8 | |
| SCHEMBL30334978 | 0.74 | RORC (0.44) | RORCGPR119PDK2HDAC1HDAC8 | |
| SCHEMBL349129 | 0.71 | HSD11B1 (0.55) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332937-A | Dipeptidyl peptidase I inhibitors and uses thereof | 杭州邦顺制药有限公司 | 2023-06-27 | — | — | CN | disclosed |