Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.46 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.46 |
| ▸ | INPP5B | P32019 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693358 | 0.84 | KDM4E (0.56) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| Hydrochloric Acid SCHEMBL28439740 | 0.82 | KDM4E (0.55) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL343312 | 0.81 | INPPL1 (0.47) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL9645945 | 0.80 | INPPL1 (0.61) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL31530599 | 0.79 | KDM4E (0.56) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL9308174 | 0.77 | INPPL1 (0.55) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL27780600 | 0.77 | ALDH1A1 (0.53) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL11726928 | 0.76 | INPPL1 (0.43) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| Sulfur Dioxide SCHEMBL28730798 | 0.75 | SLC6A3 (0.39) | ALDH1A1HSD17B10SLC6A3MEN1KMT2A | |
| Ether SCHEMBL8746888 | 0.74 | KDM4E (0.46) | INPPL1INPP5AINPP5BSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924343-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | Merck Sharp & Dohme Corp. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2010036613-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |