Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29166084 | 0.90 | LMNA (0.47) | KMT2APKMLMNAFDPSCYP3A4 | |
| SCHEMBL29715349 | 0.89 | CYP3A4 (0.42) | KMT2APKMALDH1A1NLRP3LMNA | |
| SCHEMBL23092647 | 0.89 | CYP3A4 (0.42) | KMT2APKMALDH1A1NLRP3LMNA | |
| SCHEMBL23092645 | 0.89 | CYP3A4 (0.42) | KMT2APKMALDH1A1NLRP3LMNA | |
| SCHEMBL30476807 | 0.83 | NPY5R (0.43) | ALDH1A1LMNACYP3A4HTT | |
| SCHEMBL17053690 | 0.81 | LMNA (0.49) | KMT2AALDH1A1NLRP3LMNACYP3A4 | |
| SCHEMBL7165402 | 0.79 | CTSL (0.46) | KMT2APKMALDH1A1LMNACYP3A4 | |
| SCHEMBL7240649 | 0.79 | CTSL (0.46) | KMT2APKMALDH1A1LMNACYP3A4 | |
| SCHEMBL25178734 | 0.79 | LMNA (0.50) | KMT2AALDH1A1LMNAFDPSCYP3A4 | |
| SCHEMBL15258852 | 0.78 | ALDH1A1 (0.48) | KMT2APKMALDH1A1NLRP3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164690-A1 | SMALL MOLECULE VE-PTP INHIBITORS | Ripka, Amy (US) | 2023-04-19 | — | — | EP | disclosed |