Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 13/20 | 0.39 |
| ▸ | CASP3 | P42574 | 4/20 | 0.39 |
| ▸ | SDCBP | O00560 | 2/20 | 0.39 |
| ▸ | SDC2 | P34741 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331664 | 1.00 | MAPK1 (0.39) | MAPK1CASP3SDCBPSDC2CASP7 | |
| SCHEMBL30477272 | 0.92 | SDCBP (0.44) | CASP3SDCBPSDC2CASP7CASP9 | |
| SCHEMBL25329555 | 0.92 | SDCBP (0.44) | CASP3SDCBPSDC2CASP7CASP9 | |
| SCHEMBL25329559 | 0.92 | SDCBP (0.44) | CASP3SDCBPSDC2CASP7CASP9 | |
| SCHEMBL25329465 | 0.91 | SDCBP (0.41) | MAPK1CASP3SDCBPSDC2 | |
| SCHEMBL30477328 | 0.91 | SDCBP (0.41) | MAPK1CASP3SDCBPSDC2 | |
| SCHEMBL31122073 | 0.89 | SDCBP (0.42) | MAPK1SDCBPSDC2 | |
| SCHEMBL30477300 | 0.85 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL25332033 | 0.85 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL25330760 | 0.84 | SDCBP (0.41) | CASP3SDCBPSDC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4461726-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | Innovo Therapeutics Inc. (KR) | 2024-11-13 | — | — | EP | claimed |
| CN-118510754-A | Novel isoindolinone derivative compounds as caspase inhibitors | 因诺沃治疗有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118510754-A | Novel isoindolinone derivative compounds as caspase inhibitors | 因诺沃治疗有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |