Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 5/20 | 0.44 |
| ▸ | SDC2 | P34741 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 6/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477272 | 1.00 | SDCBP (0.44) | SDCBPSDC2CASP3CASP7CASP9 | |
| SCHEMBL25329555 | 1.00 | SDCBP (0.44) | SDCBPSDC2CASP3CASP7CASP9 | |
| SCHEMBL30477289 | 0.92 | MAPK1 (0.39) | SDCBPSDC2CASP3CASP7CASP9 | |
| SCHEMBL25331664 | 0.92 | MAPK1 (0.39) | SDCBPSDC2CASP3CASP7CASP9 | |
| SCHEMBL25329465 | 0.89 | SDCBP (0.41) | SDCBPSDC2CASP3 | |
| SCHEMBL30477328 | 0.89 | SDCBP (0.41) | SDCBPSDC2CASP3 | |
| SCHEMBL25332033 | 0.83 | MAPK1 (0.39) | — | |
| SCHEMBL30477300 | 0.83 | MAPK1 (0.39) | — | |
| SCHEMBL25330760 | 0.83 | SDCBP (0.41) | SDCBPSDC2CASP3 | |
| SCHEMBL25330762 | 0.83 | SDCBP (0.41) | SDCBPSDC2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109135-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | INNOVO THERAPEUTICS INC. (KR) | 2025-04-03 | — | — | US | claimed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | claimed |
| US-20250109135-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | INNOVO THERAPEUTICS INC. (KR) | 2025-04-03 | — | — | US | disclosed |
| EP-4461726-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | Innovo Therapeutics Inc. (KR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109135-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | CASP1, CASP8, CASP2 | SDCBP 3595/4885SDC2 4311/4885CASP3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.