SCHEMBL25330760

SCHEMBL25330760

CC[C@@H](C(=O)NC(CC(=O)O)C(=O)CF)N1Cc2cc(-c3coc4ccccc34)ccc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SDCBP O00560 12/20 0.41
SDC2 P34741 12/20 0.41
CASP3 P42574 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25330762 1.00 SDCBP (0.41) SDCBPSDC2CASP3
SCHEMBL25329465 0.94 SDCBP (0.41) SDCBPSDC2CASP3
SCHEMBL30477328 0.94 SDCBP (0.41) SDCBPSDC2CASP3
SCHEMBL25330663 0.87 CASP1 (0.42) SDCBPSDC2CASP3
SCHEMBL30477273 0.87 CASP1 (0.42) SDCBPSDC2CASP3
SCHEMBL25330659 0.87 CASP1 (0.42) SDCBPSDC2CASP3
SCHEMBL25331261 0.85 SDCBP (0.38) SDCBPSDC2CASP3
SCHEMBL30477263 0.85 SDCBP (0.38) SDCBPSDC2CASP3
SCHEMBL25331258 0.85 SDCBP (0.38) SDCBPSDC2CASP3
SCHEMBL25331664 0.84 MAPK1 (0.39) SDCBPSDC2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250109135-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS INNOVO THERAPEUTICS INC. (KR) 2025-04-03 US claimed
EP-4461726-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS Innovo Therapeutics Inc. (KR) 2024-11-13 EP claimed
US-20250109135-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS INNOVO THERAPEUTICS INC. (KR) 2025-04-03 US disclosed
EP-4461726-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS Innovo Therapeutics Inc. (KR) 2024-11-13 EP disclosed
WO-2023132606-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS 주식회사 이노보테라퓨틱스 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109135-A1 NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS CASP1, CASP8, CASP2 SDCBP 3595/4885SDC2 4311/4885CASP3 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.