Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148942 | 1.00 | HDAC6 (0.48) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27764496 | 0.85 | HDAC6 (0.50) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL413572 | 0.83 | NAPRT (0.58) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29488337 | 0.83 | NAPRT (0.58) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24314845 | 0.83 | HDAC6 (0.43) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18033657 | 0.81 | HDAC6 (0.48) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL628397 | 0.81 | PARP1 (0.51) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29687007 | 0.81 | PARP1 (0.51) | HDAC6NAPRTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29646334 | 0.81 | P2RX7 (0.58) | HDAC6NAPRTALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL1447540 | 0.81 | P2RX7 (0.58) | HDAC6NAPRTALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638619-A | Indan pyridine amide compound and preparation method and application thereof | 盐城工学院 | 2025-03-18 | — | — | CN | disclosed |
| CN-119176800-A | Pyridine thiophene acetamide compound and preparation method and application thereof | 盐城工学院 | 2024-12-24 | — | — | CN | disclosed |
| CN-111741945-B | Crystalline forms | 先正达参股股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111417618-B | Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides | 先正达参股股份有限公司 | 2023-06-30 | — | — | CN | disclosed |