Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800830 | 0.79 | SMN1; SMN2 (0.34) | IDO1ALDH1A1ALOX15 | |
| SCHEMBL9257656 | 0.79 | MAPK1 (0.40) | CYP3A4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL10918770 | 0.78 | KIF11 (0.40) | CYP19A1PKMKIF11CYP3A4IDO1 | |
| SCHEMBL1859294 | 0.73 | KIF11 (0.44) | CYP19A1PKMKIF11CYP3A4SCN5A | |
| Hydrochloric Acid SCHEMBL16321424 | 0.71 | KIF11 (0.43) | CYP19A1PKMKIF11CYP3A4IDO1 | |
| SCHEMBL8661448 | 0.71 | GRM5 (0.35) | CYP19A1PKMSCN5ASCN9A | |
| SCHEMBL3356661 | 0.70 | ALDH1A1 (0.50) | CYP19A1KIF11CYP3A4IDO1AGXT | |
| SCHEMBL3978179 | 0.70 | KIF11 (0.45) | CYP19A1PKMKIF11SCN5ASCN9A | |
| SCHEMBL3960158 | 0.70 | KIF11 (0.45) | CYP19A1PKMKIF11SCN5ASCN9A | |
| SCHEMBL6074031 | 0.70 | CYP19A1 (0.47) | CYP19A1PKMKIF11SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437915-B | Crystal form of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118871442-A | Crystal form of fumarate of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113544131-B | Pyrrolo-heterocyclic derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-116437915-A | Crystal form of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114315837-B | Crystalline forms of ERK inhibitors and methods of making the same | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |